Clean in Place Recipe Optimization
Marin Alvarez, Crystal
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This improvement project was based in reduce the fixed tanks and transfer lines Clean in Place (CIP) recipe execution by consolidating the Water for Injection (WFI) rinse and the WFI CIP recipes into one single recipe. This new recipe was used when system is employed for WFI collection and buffer preparation processes. DMAIC methodology was used as a tool to present the information required for the project. Is a series of steps used to measure the waste in an industry and improve the efficiency of it. These steps are Define, Measures, Analyze, Improve and Control. After implementation, a standard work was generated to be aligned with the time expected for each stage of the process. In general, the project obtained successful results reducing the new recipe 21% after the optimization performed in the process. Key Terms ⎯ Recipe, CIP, Cycle time, and DMAIC methodology.