• Clean Room Differential Pressure Monitoring Improvements 

      Vázquez Amaro, Luis J. (Polytechnic University of Puerto Rico, 2019)
      Manufacturing of oral solid dosage (OSD) forms, such tablets and capsules, is performed in a highly regulated environment. One of the guidelines used to provide the minimum requirements that a manufacturer must meet ...
    • Design Methodology of Clean Room Overtime Reduction in a Medical Device Plant 

      Pabellón Díaz, Yaxaira E. (Polytechnic University of Puerto Rico, 2015)
      According to the last year data in a medical device company, the packaging shipped units are increasing by the last eight months. The packaging clean room headcount are generate too much overtime affecting the finance ...
    • Enhancements to Cardinal Health NPS Lab to USP-787 Standards 

      Figueroa Rodriguez, Jose A. (Polytechnic University of Puerto Rico, 2020)
      As the world develops and populations expand, new diseases arise at an exponential rate. This research is based on employing new modifications to NPS (Nuclear Pharmacy Services) Laboratory at Cardinal Health, Inc. ...
    • Optimizing Automated Clean-In-Place Operations to Increase Productivity in a Biotechnology Manufacturing Plant 

      Villanueva González, Rhyan S. (Polytechnic University of Puerto Rico, 2016)
      Automated Clean-In-Place Operations are an essential part of the manufacturing operations by ensuring a clean state of the equipment and/or transfer lines. However, during a voice of the customer (VOC) and value-adde ...
    • Surgical Technologies Clean Room Lines Capacity Improvement 

      Cruz Feliciano, Gabriela A. (Polytechnic University of Puerto Rico, 2015)
      In today’s competitive market, medical device manufacturing companies need to continuously innovate their products and process in order to maintain a leader position on the medical devices industry. Quality and Cost ...