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Reducción del Tiempo de Cambio para la Línea de Empaque#5
(Polytechnic University of Puerto Rico, 2018)
Se utiliza la técnica de Lean
Manufacturing con la metodología DMAIC para
reducir el tiempo de cambio o Changeover de la
línea de empaque#5. Para llevar a cabo su
implementación se midieron las fases de
culminación ...
Application of Lean Manufacturing and Lean Six Sigma Tools to Improve Back to Back Activities in the Compression Process
(Polytechnic University of Puerto Rico, 2019)
A recent opportunity regarding a
product ramp up in the production schedule due to
a potential product transfer requires the
manufacturing area to look for creative ways to
improve in order to comply with expected ...
In-Process pharmaceutical manufacturing aqueous coating suspension hold time study
(Polytechnic University of Puerto Rico, 2018)
A hold time study is established in the
development phase of any product. All the InProcess unit operations require a hold time study to
protect the integrity and quality of the final drug
product. This study will analyze ...
Changeover Reduction Time by Adjusting the Cleaning Critical Parameters in Automated CIP Systems
(Polytechnic University of Puerto Rico, 2018)
Clean-In-Place (CIP) is a widely use
process to clean biotechnology vessels contact
surfaces. CIP is an automated cleaning method that
involve minimum to no equipment disassembling
thereby reducing labor and time ...
Optimization of the Registration Process of Products on the Pharmaceutical Industry of Puerto Rico
(Polytechnic University of Puerto Rico, 2018)
Registration Process for
pharmaceutical products in Puerto Rico has unique
requirements for the marketing, sale, and
distribution of the products. The Organizations
must be approved before they can market, sell ...
Reducing Downtime Due to Glove Breakage in Manufacturing Areas
(Polytechnic University of Puerto Rico, 2022)
Lean manufacturing was developed for maximizing resource utilization through the minimization of waste. During certain tasks in the Manufacturing Area, gloves tended to break. I propose that we need to reduce the walk ...
Standardization Times in a Blending (Flex 2 Unit Operation) Manufacturing Process
(Polytechnic University of Puerto Rico, 2023)
The continuous evolution in standardization, digitalization, and changes in the ways of working in manufacturing in the
pharmaceutical industry and the increase in production for product X by 2023, has made it necessary ...
Using Six Sigma Methodology and Technology to Improve Quality Audit Process Cycle Time
(Polytechnic University of Puerto Rico, 2022)
Currently, at the “Pharmaceutical Company Y”, the cycle for launching a product can take an average of 46.7 days. The proposal for this study seeks to reduce this cycle time to 30 days. This project illustrates the ...
Unidirectional Flow Gasket
(Polytechnic University of Puerto Rico, 2022)
To reduce the number of deviations that occur annually in the plant, through a design, it is expected to reduce this problem taking into consideration the cost factor, lead time and the quality of the products made. Using ...
Redesign of a Space in the Autopsy Room Assigned for the Preparation of Biological Samples for Toxicological Analysis by Using DMADV Technique
(Polytechnic University of Puerto Rico, 2022)
The government agency of the Institute of Forensic Sciences recently received the necessary accreditations to be able to provide the essential service it offers to the citizens of Puerto Rico. The objective of this project ...