Manufacturing Engineering
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Recent Submissions
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Improvement of Predictive Model to Reduce Impurity Presence Based on Raw Material Combination Pre-Selection
(Polytechnic University of Puerto Rico, 2023)Biotechnology manufacture is composed of two main sections, Active Pharmaceutical Ingredient (API) and Drug Product (DP). The DS manufacturing most common steps are cell culture or fermentation (DSI), recovery and purification. ... -
Optimization of Bioburden Samples Processing in the Microbiology Laboratory Using Six Sigma
(Polytechnic University of Puerto Rico, 2023)This article presents the use of the Lean Six Sigma tool to identify factors affecting the processing of samples that require Bioburden testing in the Microbiology Laboratory. The objective of this article was to implement ... -
Improvement and Design of a Kitchen Using DMADV Methodology
(Polytechnic University of Puerto Rico, 2023)This design project will focus on remodeling a kitchen for an elderly person. The kitchen that is going to be remodeled has a peninsula or G-shaped layout design. The new design that will be introduced aims to save time ... -
Reduce Scrap for Kiefel Machine Non-PVC
(Polytechnic University of Puerto Rico, 2023)The bag-making process is performed in different locations globally. IV Bags are used worldwide for various treatments. This project aims to reduce the scrap from the Non-PVC machine. This is the only one of ten department ... -
Manufacturing of a Continuous Line of Salbutamol Tablets Through the Methodology of DMADV
(Polytechnic University of Puerto Rico, 2023)This project aimed to enhance the production process of salbutamol by designing and implementing a continuous production line using the DMADV methodology. The study objectives were to establish proper visualization of the ... -
Construction Services Company – Purchases Process and Warehouse System Improvements
(Polytechnic University of Puerto Rico, 2023)In the manufacturing industry, engineers focus on positively impacting all areas related to product output. When the output is tangible, several methodologies and assessments can be implemented to improve the production ... -
Product Mix Analysis in Manufacturing Line
(Polytechnic University of Puerto Rico, 2023)This research project was focused on the Product Mix Analysis of a Medical Device manufacturing line due to a customer complaint. A product mix is a manufacturing defect and is defined as a mix of components/ assembly ... -
Sistema de Validación, Comisionar y Cualificar en la era Digital
(Polytechnic University of Puerto Rico, 2023)Este proyecto es basado en la investigación creación de documento dentro una nueva de la nueva implementación de un programa para la validación digital en las industrias de BioFarma y Medical Device. Esta nueva plataforma ... -
IV Bag Fill Volume Project
(Polytechnic University of Puerto Rico, 2023)Accurate filling of intravenous (IV) bags is a critical aspect of healthcare, ensuring patients receive the precise medication dosage while minimizing wastage and reducing costs. The existing IV bag filling process often ... -
Small Business Lean Inventory Optimization
(Polytechnic University of Puerto Rico, 2023)This research investigates the problem of ineffective inventory management systems in small businesses using a qualitative case study approach. The study focuses on Dixon's Refrigeration, identifying the root causes of ... -
Identification of Contributing Factors Impacting Aircraft Engine Component Repair Instructions Development
(Polytechnic University of Puerto Rico, 2022)The development of repair instructions for aircraft engine components is complex and vulnerable to errors during development, affecting the completion and delivery on a timely manner. The purpose of this project was to ... -
Causas de la pérdida de leche en una vaquería localizada en Puerto Rico
(Polytechnic University of Puerto Rico, 2022)En este proyecto de investigación se analizaron las causas de la pérdida de leche en las vacas, específicamente en una vaquería ubicada en Moca. Se analizó el proceso de ordeño de la vaca y el uso del robot Lely Astronaut ... -
Process Characterization of Thermal Bond Process
(Polytechnic University of Puerto Rico, 2022)Process Characterization is a required step in the commercialization of a new product. The intent of this process characterization is to ensure that the Midjoint Thermal Bond manufacturing process delivers a consistent ... -
Automatization of the Patch and Serter Installation System’s Sensor Transference Step
(Polytechnic University of Puerto Rico, 2022)The Patch and Serter Installation System is one of the multiple computerized systems that composes the Cell Operating System (COS) assembly lineat Medtronic Juncos Campus as part of the Project Synergy. This equipment ... -
Reducing the amount of "turnback" on the classification center
(Polytechnic University of Puerto Rico, 2022)The research Reducing the Amount of “Turnback” on the Classification Center consists in the large amount of turnbacks that occur on the database system on a daily basis these turnbacks are errors that affect the time service ... -
Statistical Sampling Plan Alternatives for Seal Strength Testing on Pre-sealed Tyvek® Bags
(Polytechnic University of Puerto Rico, 2022)Seal strength is an important quality of sterile barrier systems used for Pharmaceutical and Medical Device Packaging operations, and subject to strict quality control industry-wide. This study evaluated the feasibility ... -
Improve HTS and Schedule B Classification Process to Reduce the Turnaround Time in a Commodity Shipments Compliance Project
(Polytechnic University of Puerto Rico, 2022)The HTS and Schedule B classification process adds two days to the turnaround time of the standard process of the Commodity Shipments Compliance team. Throughout 2021, 108 of 326 requests approvals, requiring HTS ... -
Manufacturing Process Coordination through Visual Analytics Tools
(Polytechnic University of Puerto Rico, 2022)This research project was focused on the identification of requirements and the design of a software application toolset, which facilitates and improve the coordination of pharmaceutical manufacturing production steps. The ... -
The Implementation of an Asset Tracking System for Manufacturing Laboratory Applications
(Polytechnic University of Puerto Rico, 2022)Globalization and technological advances had made industries to implement systems in which the outcome could be reflected in their competitiveness. Most of the industries incorporates laboratories within their structure ... -
Lean Manufacturing Implementation to Improve Process Capability and Performance
(Polytechnic University of Puerto Rico, 2022)Industries has been continuously evolving with the change in tendencies and market growth of products. To be capable of maintaining the organization competitiveness, in front of an aggressive market, ...
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