Now showing items 29-48 of 323

    • Capability of CNC-Mori-Seiki ENDO HEAD 

      Castillo Rodríguez, José L. (Polytechnic University of Puerto Rico, 2016)
      Endo Head is a product suitable to perform hemiarthroplasty on any hip joint whose acetabular conditions are satisfactory. The Endo Head is a unipolar prosthesis made of CoCr alloy that consists of a Monobloc prosthetic ...
    • Clean Room Differential Pressure Monitoring Improvements 

      Vázquez Amaro, Luis J. (Polytechnic University of Puerto Rico, 2019)
      Manufacturing of oral solid dosage (OSD) forms, such tablets and capsules, is performed in a highly regulated environment. One of the guidelines used to provide the minimum requirements that a manufacturer must meet ...
    • Combination Products Regulation – A Guide to Compliance 

      Cabranes, Leo R. (Polytechnic University of Puerto Rico, 2015)
      The Food and Drug Administration (FDA or Agency) has issued a regulation on the current good manufacturing practices (CGMP’s) requirements applicable to combination products. The new rule is intended to promote the ...
    • Complaint Reduction Project of Infant Heel Incision Lancets of a Medical Device Manufacturing Plant 

      Rodríguez González, José G. (Polytechnic University of Puerto Rico, 2017)
      The purpose of this project was to identify key factors affecting the complaint rate of the infant heel stick lancet related to insufficient blood flow from the incisions and no activation of the lancet after triggered. ...
    • Compression Machines Relocation for Space Optimization 

      Velazquez del Valle, Omar (Polytechnic University of Puerto Rico, 2013)
      Pharmaceutical industries develop, produce and market drugs for use as medications. All pharmaceutical manufacturers are directed to produce in a high optimization environment to increase productivity and ensure product ...
    • Computer System Validation CSV in Data Integrity Implementation Strategies for Pharmaceutical Industry 

      Colón Nazario, Alexis (Polytechnic University of Puerto Rico, 2018)
      Computer System Validation CSV in Data Integrity refers to the completeness, consistency, and accuracy of data. Complete, consistent, and accurate data should be attributable, legible, contemporaneously recorded, original ...
    • Continuous Improvement in a Warehouse of Short Bark Industries 

      Delgado Orta, Giovanni M. (Polytechnic University of Puerto Rico, 2013)
      In the company Short Bark Industries is manufacturing military clothing and accessories. This company has a problem in the organization and excess inventory in the warehouse. For this they need to implement two Lean ...
    • Continuous Manufacturing Variability Study 

      Lozada Vázquez, Melissa (Polytechnic University of Puerto Rico, 2016)
      Continuous manufacturing variability is measured with the help of analysis of variance methodologies and statistical process control (SPC) tools such as control charts. The objective of this project was to assess ...
    • Control Strategy design of a Continuous Direct Compression Process for Oral Solids Dosages using Resident Time Distribution Studies 

      Almodovar Garcia, Elvin O. (Polytechnic University of Puerto Rico, 2021)
      In a continuous process any deviation from the intended process parameters can cause an unreliable product and economical losses.Residence time is a measure of how much time any given material or ...
    • Coronary Guide Wires Abbott Vascular 

      Espinell Marquez, Edwin (Polytechnic University of Puerto Rico, 2019)
      Abbott Vascular produces guide wires which are designed to navigate vessels to reach a lesion or vessel segment. Once the tip of the device arrives at its destination, it acts as a guide so that larger catheters can ...
    • Cost & Cycle Time Reduction and Increased Production on CNC Machines 

      Bosques Cardona, Darien J. (Polytechnic University of Puerto Rico, 2014)
      There are a lot of different types of manufacturing industries. Some of the similarities, in the majority, is the need to reduce cost, cycle tyme and consequently increase productivity. There are several methodologies ...
    • Cost and Safety Benefits when Implementing the Analytical Condition Inspection (ACI) Program on the F-35A (Lightning II) Fleet 

      Pabón Martínez, José D (Polytechnic University of Puerto Rico, 2018)
      In 2012 [1], the first F-35A’s (conventional takeoff and landing) [2] fighter jets took off the production line to join the US Air Force (USAF) fleet. Since then, this weapons system has flown in multiple missions ...
    • Cost Reduction in the Accumulator Process in Welding Operations 

      Santiago Nieves, Igmel (Polytechnic University of Puerto Rico, 2015)
      For the last few weeks, the heating, ventilation, and air conditioning manufacturing company Thermo King Arecibo has been increasing the operational cost due to leak problems on the accumulator area in the welding ...
    • Creation of a Library for a Religious Organization Using the Lean Six Sigma Methodology 

      Torres, Ivette (Polytechnic University of Puerto Rico, 2011)
      Abstract - Due to the economic situation during this 21th century, each individual, corporation, industry, service, and any kind of business, is looking for better ideas to improve their day to day jobs. It is not a surprise ...
    • CSV Program Implementation using a Risk Based Approach to align ICH with GAMP5 

      Miranda Narváez, Hiramdie (Polytechnic University of Puerto Rico, 2016)
      it has been 29 years when Process Validation was created. Since then there has been a lot of creations of different types of validations. During the years there have been a lot of improvements in every validation ...
    • Cycle Time Reduction of a Crystallization Process in a Chemical Plant 

      Monroig, Cyd Marie (Polytechnic University of Puerto Rico, 2013)
      Estimates indicate that Diabetes will increase affecting the population worldwide in the future. To mitigate current and future demand, Barceloneta’s Factory 2 needs to improve the active pharmaceutical ingredient (API) ...
    • Cycle Time Reduction using Lean Manufacturing Techniques for a Solid Pharmaceutical Product 

      Ocasio Ortiz, Ángel (Polytechnic University of Puerto Rico, 2009)
      Abstract ⎯ The purpose of this project was to demonstrate that the Lean Manufacturing techniques could be applied to a Solid Pharmaceutical Product in order to reduce the cycle time. During the year 2007, the Solid ...
    • Data Integrity Implementation Strategy for Pharma Industry 

      Cádiz García, Osvaldo R. (Polytechnic University of Puerto Rico, 2017)
      Data integrity is fundamental in a pharmaceutical quality system which ensures that medicines are of the required quality as decisions on product quality are made based on the data. Electronic data and computerized ...
    • Database for Collection of Defects in Main Line Production in Electrical Manufacturing 

      Mercado Dávila, Yareelis (Polytechnic University of Puerto Rico, 2016)
      This project was developed in order to create a database to analyze of the major defects identified when the quality representative realizes inspections in the main line of an Electrical Manufacturing firm. A database ...
    • Database Update Automation for a Service Company Applying DMAIC 

      Cortés Pujols, Francis (Polytechnic University of Puerto Rico, 2012)
      Abstract – Working in a service oriented engineering organization, delivery, quality and cost reduction, are very important for a competitive and successful environment, managing data and present reports to their clients ...