• Development of a New Medical Device Production Line Using Systems Engineering 

      Pereira Williams, José E. (Polytechnic University of Puerto Rico, 2012)
      Abstract - The design and development of a production line to manufacture a new medical device for clinical trials requires the establishment of a very precise implementation plan. This is especially important since we are ...
    • Development of an Automated System for the Monitoring and Control pH and Conductivity of a Dampening Solution 

      León Alvarez, Ivelisse (Polytechnic University of Puerto Rico, 2012)
      The influence of dampening solution parameters on the final printing quality has been remarked on many researches during the last decades. There are many parameters that need to be controlled on a fountain solution as pH, ...
    • Development of Bulk Shipping Studies in Pharmaceutical Industry 

      Marrero Ruiz, Josean O. (Polytechnic University of Puerto Rico, 2012)
      Abstract ⎯ A bulk shipping study in the pharmaceutical industry consists in monitoring and analyzing the environmental conditions (e.g. temperature and relative humidity) during shipping and transportation of the drug ...
    • Development of Dual Drugs with Coated Microneedles 

      Pérez Figueroa, Alexander G. (Polytechnic University of Puerto Rico, 2022)
      Coated microneedles have been shown to deliver biopharmaceuticals and drugs into the skin in a minimally invasive manner. To increase patient acceptance, smaller needle diameters and lower insertion ...
    • Development of Effectiveness Program through the Use of Productivity Metrics 

      Rosario, Brenda L. (Polytechnic University of Puerto Rico, 2014)
      The Overall Plant Effectiveness Program has the purpose to improve the production capacity and optimize operations performance in an Active Pharmaceutical Ingredient (API) manufacturing plant. It requires a complete analysis ...
    • Diseño de Optimización en el Proceso de Diseño en el Área de Moldeo por Inyección 

      Rivera Hernández, René G. (Polytechnic University of Puerto Rico, 2017)
      Mediante el uso de la metodología de Lean se reduce el tiempo de diseño y al mismo tiempo se eleva la calidad de producto que se hace en los moldes de inyección. Este método se aplicará haciendo una implementación de ...
    • Diseño de Optimización en Logística de Organización 

      Rapale González, Fransheska (Polytechnic University of Puerto Rico, 2018)
      El presente trabajo se desarrolló con la finalidad de implementar la metodología DMAIC Seis Sigma en conjunto a la de 5s, organizando y limpiando para reducir el tiempo que toma la búsqueda de materiales y herramientas ...
    • Diseño de Proceso de Retorno de Componentes Funcionales de Dispositivos Médicos 

      Madera Reyes, Lorraine (Polytechnic University of Puerto Rico, 2016)
      El uso de un dispositivo médico es más común día tras día. El constante aumento en producción aumenta además la acumulación de unidades fallidas en el área de manufactura. Cada proyecto de creación para una línea ...
    • Diseño de Procesos de Mejora para obtener un “PMA” del FAA 

      Galloza Avilés, Antonio (Polytechnic University of Puerto Rico, 2016)
      Actualmente existe mucha competencia entre compañías que realizan servicios similares, haciendo imperativo el buscar formas para poder mejorar los procesos de los productos que las mismas ofrecen, haciéndolos más ...
    • Downstream Sampling Process Optimization 

      Joshi Sánchez, Atika N. (Polytechnic University of Puerto Rico, 2014)
      The Downstream Sampling Process in the Biopharmaceutical industry is a timely and product consuming step. This process can be described as a highly labor intense due to all the required steps to collect a sample. In ...
    • Downtime Reduction Driven by Evaluation of Material Unavailability 

      Rivera Garcia, Danny (Polytechnic University of Puerto Rico, 2014)
      In the manufacturing & life-sciences industry, increased competition has forced a cost-reduction philosophy in what was once a highly profitable business. Manufacturers now need to maintain or improve time to market and ...
    • Effective Work Order Requests And Scheduling Tool Design for Maintenance Jobs 

      Vélez Arias, Sergio A. (Polytechnic University of Puerto Rico, 2020)
      A company located in Puerto Rico, which provides maintenance services and project management for various private properties, identified a problem of delays in maintenance work order response time and completion of ...
    • Effectiveness of Push-Pull Method in a Hydraulic Sales Environment 

      Ortiz Burgos, Juan R. (Polytechnic University of Puerto Rico, 2016)
      In today industry of sales, the main activity is to manage inventory in the fastest way possible. In the same way a warehouse main activity is to move the inventory from point a to point b in the fastest way without ...
    • Electronic Report Improvement Using Six Sigma DMAIC Tools 

      Pérez Acosta, Javier A. (Polytechnic University of Puerto Rico, 2011)
      Abstract - The purpose of this project is to evaluate the application and benefits of Six Sigma tools to electronic reporting. In this particular case the DMAIC (Define, Measure, Analyze, Implement and Control) method is ...
    • Electrospinning Process Capacity Optimization In Medical Device Industries 

      Rivera González, Freddie Joel (Polytechnic University of Puerto Rico, 2021)
      As part of the manufacturing cost reduction initiatives that support 2021 Operational Excellence Projects to promote continuous improvement on medical device industries; the Electrospinning (E-spin) process was found with ...
    • Emotional Intelligence of Project Management Engineers in Puerto Rico: Profile Insights 

      Rojas García, Hiram (Polytechnic University of Puerto Rico, 2012)
      Abstract ⎯ Although most Project Management Professionals agree that emotional intelligence is of paramount importance in addressing a project’s human factor, few studies exist that shed light on the emotional intelligence ...
    • Enfoque Estratégico para la Realización de Pruebas de Coeficiente de Reparto en el Desarrollo de Suplementos Dietéticos 

      Cruz Cruz, Christian H. (Polytechnic University of Puerto Rico, 2017)
      El aumento en sobrepeso de la población es una situación que ha estado arropando gran parte de la población mundial en especial a los países latinoamericanos. Esto acarrea consigo múltiples factores de riesgo y puede ...
    • Engineering Standard Work Proficiency Reports Automation for the Aerospace Industry 

      Morales Quiles, Luis (Polytechnic University of Puerto Rico, 2012)
      Abstract - The study was conducted in an Aerospace Industry located in Isabela, Puerto Rico. The objectives of this project were to eliminate report errors and to reduce the report development from 5 days to less than 1 ...
    • Engineering Study for the Feeding Operation Process of a Continuous Manufacturing Line 

      Classe Miranda, Gustavo (Polytechnic University of Puerto Rico, 2016)
      The use of continuous operations in solid-dosage manufacturing is growing rapidly and bringing benefits within pharmaceutical industry. One of the benefits that the continuous operation provides is that the development ...
    • Enhance Annual Product Review Process at Pharmaceutical Company in Puerto Rico 

      Rivera Martínez, Lynnette (Polytechnic University of Puerto Rico, 2014)
      Annual Product Review (APR) is a requirement from Good Manufacturing Practices (cGMP) under the FDA (Food and Drug Administration) and European Medicine Agency (EMEA). The EMEA refers to Annual Product Quality Review ...