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Wet Granulation End-Point Determination of a Drug Formulation
(Polytechnic University of Puerto Rico, 2019)
Wet granulation is commonly used in
oral solid dosage industry. The end-point is required
to design a process that consistently meet products
Critical Quality Attributes (CQAs) and the Critical
Processing Parameters ...
Optimization of Tooling Design Process for Assembly of Motor Parts
(Polytechnic University of Puerto Rico, 2019)
This project developed a DMAIC process
to start improving the results of a new task been
performed in the company [1]. The project will
focus on improving the quality and turnaround time
of the work performed. the ...
Lean Implementation in a Turbocharger Service Shop
(Polytechnic University of Puerto Rico, 2014)
In many of the manufacturing and
repair shops, the use of industrial machinery is
required to perform most production or repair
efforts. A Turbo Service repair shop was identified
due to its needs of Lean tools and ...
Applying a Quality Risk Management Approach to a Cleaning Validation System
(Polytechnic University of Puerto Rico, 2014)
Cleaning Validation is a crucial step
on assuring product effectiveness and safety by
assuring that the equipment to be used has the
appropriate condition to manufacture a new
product without any foreign substances ...
Use of Quality Management Tools to Improve the Operations of a Flag Production Company
(Polytechnic University of Puerto Rico, 2014)
The objective of this research is to
improve the operations of a Flag Production
Company by the use of Quality Management
techniques. Small companies have been struggling
these days on being competitive against big ...
Visual Basic as a Tool for the Automation of Engine Health Monitoring Systems in the Aerospace Industry
(Polytechnic University of Puerto Rico, 2014)
The aerospace industry presents many
challenges when it comes to provide quality and
reliability to its users. Many lives depend on the
appropriate maintenance and on-time delivery of
products and services on a daily ...
Improvement of Contact Lens Field Complaint Rate Using the DMAIC Approach
(Polytechnic University of Puerto Rico, 2009)
Contact lenses are susceptible to a
defect call “tearing”. This is common but seldom
condition detected in the field by the customer. The
manufacturing process of a contact lens is a very
precise method of combining ...
Risk Prevention in Syringe Filling Line in a Pharmaceutical Manufacturing Plant
(Polytechnic University of Puerto Rico, 2013)
Risk prevention in syringe filling line
can be achieved through the implementation of
“Defense in Depth” concepts. Defense in Depth is
based on the integration of 3-layers of operational
controls which are Equipment, ...
Finished Goods Failure Reduction in a Wound Closure Medical Device Product Family
(Polytechnic University of Puerto Rico, 2013)
A corrective action and preventive
action plan was developed to address the increase
of Finished Goods failures in a wound closure
medical device product family. Following a DefineMeasure-Analyze-Improve-Control Six ...
Compression Machines Relocation for Space Optimization
(Polytechnic University of Puerto Rico, 2013)
Pharmaceutical industries develop,
produce and market drugs for use as medications.
All pharmaceutical manufacturers are directed to
produce in a high optimization environment to
increase productivity and ensure product ...