• español
    • English
    • Deutsch
  • English 
    • español
    • English
    • Deutsch
  • Login
View Item 
  •   PRCR Home
  • Polytechnic University of Puerto Rico
  • Design Project Articles Master Degree
  • Manufacturing Competitiveness
  • View Item
  •   PRCR Home
  • Polytechnic University of Puerto Rico
  • Design Project Articles Master Degree
  • Manufacturing Competitiveness
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Optimization of On-Line Automated Dissolution System for Solid Dose Control Release Tablets

Thumbnail
View/Open
SP-09_Articulo Final_Cruz Marrero (186.3Kb)
Date
2009
Author
Marrero Teruel, Cruz M.
Metadata
Show full item record
Abstract
Abstract ⎯ An optimization of an automated dissolution system for control release tablets has been accomplished by the implementation of several variables using Six Sigma tools. Variables under evaluation includes: filter retention, baselines verification and addition of system suitability parameters. The implementation of the analyzed variables were compare before and after the optimization within 95% confidence interval generating statistically difference between them for three (3) out of four (4) sampling points. Additionally, after the statistical evaluation of the changes the dissolution profiles were evaluated by dissolution similarity factor (f2) test, where the improvements shows an increase of fifteen (15) units against the same test before the implementation of the optimization. Key Terms ⎯ Control Release Tablets, Dissolution profile, UV/VIS Spectroscopy.
URI
http://hdl.handle.net/20.500.12475/933
Collections
  • Manufacturing Competitiveness

PRC Repository copyright © 2023  COBIMET, Inc.
Contact Us
Theme by 
Atmire NV
 

 

Browse

All of PRCRCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

My Account

LoginRegister

Statistics

View Usage Statistics

PRC Repository copyright © 2023  COBIMET, Inc.
Contact Us
Theme by 
Atmire NV