• Smart Camera Mimics Humans Decision Making Process in a Vial Crimp Quality Automated Inspection Process 

      Delgado, Jorge R. (Polytechnic University of Puerto Rico, 2013)
      Crimp quality is an important attribute in the vial filling process. It protects the sterility of the product from manufacturing until it is dispensed. A pharmaceutical company performed a Failure Mode and Effect ...
    • Medical Device Assembly Yield Improvement: Application of Quality Foundations 

      Rufino Nina, Kenneth J. (Polytechnic University of Puerto Rico, 2013)
      Quality foundations application is not a new concept for medical device, manufacturing, and service industries. The key quality concepts have origins from the quality pioneers named as “gurus” Joseph Juran, Deming and ...
    • Implementing a Compressed Air Leak Preventive and Repair Program 

      Menéndez Figueroa, Melvin (Polytechnic University of Puerto Rico, 2013)
      In recent years the energy cost in Puerto Rico has been constantly increasing. The reasons vary from more expensive fuel costs, new environmental regulations requirements and inefficiencies in the system. The major ...
    • Training Process Standardization in the Configuration of a Mobile Marketing Tool using PDCA Methodology 

      Novosel Rodriguez, Nivia M. (Polytechnic University of Puerto Rico, 2013)
      For the last few years, mobile marketing has become a very powerful tool to improve business revenues. This is an extension of internet marketing, with more people spending time on their mobile devices and less in their ...
    • Dermabond Automation- Mini Swab Assembly Machine 

      Bernis Vazquez, John (Polytechnic University of Puerto Rico, 2013)
      This project covers the development, design and process control of Dermabond Mini Swab Assembly Machine. The project focused primarily on a solution based on the automation and process control application. This report ...
    • Increase Productivity in a Manufacturing Department of a Medical Devices Company 

      Aponte Nunez, Jonathan (Polytechnic University of Puerto Rico, 2013)
      In all companies the productivity is a very important metric because is the way to make sure that we optimize our resources and time. Is the way to measure if we are manufacturing as expected and with the required ...
    • H&K Capsule Filling Equipment Reliability 

      Iglesias, Victor (Polytechnic University of Puerto Rico, 2013)
      Encapsulation is a process whereby the dose is charged into a hard gelatin capsule; powder, pellets, tablets or combinations of two or more of these may be filled into the capsules. Capsules provide a convenient way ...
    • Quality Improvement of a Paint and Restoration Process in the Remanufacturing Industry 

      Llanos Henriquez, Gabriel E. (Polytechnic University of Puerto Rico, 2013)
      In a remanufacturing operation it was required to improve the first pass yield of a Paint and Restoration process that handles plastic and metallic parts. The raw material for the process is recovered from used household ...
    • Reduction in Dissolution Test Results Variability of A/B Capsule Product 

      Casiano Parrilla, Edgar (Polytechnic University of Puerto Rico, 2013)
      Since the origins of the agency, the Food and Drugs Administration (FDA), a scientific, regulatory, and public health agency had been dedicated to consumer protection. The FDA, provides standardized regulations and ...
    • Manufacturing Process Optimization for a Small Scale Craft Brewery 

      Rivera Vélez, Ashleen Marie (Polytechnic University of Puerto Rico, 2013)
      This research empirically examines the process of craft beer manufacturing in a newly established Microbrewery. Craft beer is the fastest growing segment, with an increase in sales of 151% from 2011 to 2012. This ...
    • Optimization of a Packaging Work Cell in a Medical Devices’ Manufacturing Plant 

      Tavarez, Cesar B. (Polytechnic University of Puerto Rico, 2013)
      This project was focused in the optimization of a packaging process within a medical device industry. The purpose was to improve secondary packaging process case packing, from a totally manual process to a fully automated. ...
    • Cycle Time Reduction of a Crystallization Process in a Chemical Plant 

      Monroig, Cyd Marie (Polytechnic University of Puerto Rico, 2013)
      Estimates indicate that Diabetes will increase affecting the population worldwide in the future. To mitigate current and future demand, Barceloneta’s Factory 2 needs to improve the active pharmaceutical ingredient (API) ...
    • Anti-inflammatory Drug Elution Rate Variability Reduction 

      Aponte Medina, Edneris (Polytechnic University of Puerto Rico, 2013)
      This project was focused in the Drug Elution Rate Variability of an Anti-inflammatory Drug used in a Medical Device Company. The project is based on the manufacturing and bonding process of a DXA Drug Collar that is a ...
    • Potable Water Quality Improvement in a Water Filtration Plant Facility 

      Hernández Rodríguez, Dori A. (Polytechnic University of Puerto Rico, 2013)
      The processes used for treatment in water plants depend on the quality of the source and the desired quality of the water. The chemicals selected for the treatment depend on the effectiveness to obtain the desired ...
    • Margin Increase as a Function of Quote Precision Optimization for Packaging Automation Projects and Services 

      Ortega Colon, Luz S. (Polytechnic University of Puerto Rico, 2013)
      This document describes design and development of quote optimization process using margin increase as a critical process response. It analyzes the aspects of estimating project or service in the packaging machinery ...
    • First Pass Yield Improvement on Casting Cell Using DMAIC Methodology 

      Peña Méndez, Luis (Polytechnic University of Puerto Rico, 2013)
      This research project was focused in the First Pass Yield improvement in a cell of a Medical Device Company. The first pass yield is defined as the number of units coming out of a process divided by the number of units ...
    • Cost & Cycle Time Reduction and Increased Production on CNC Machines 

      Bosques Cardona, Darien J. (Polytechnic University of Puerto Rico, 2014)
      There are a lot of different types of manufacturing industries. Some of the similarities, in the majority, is the need to reduce cost, cycle tyme and consequently increase productivity. There are several methodologies ...
    • Design a Predictive Control Model for a CIP System 

      Santiago Santos, Pablo A. (Polytechnic University of Puerto Rico, 2014)
      This document describes the analitical method to define control parameters during a clean in place (CIP) cicle in the pharamaceutical/food industry. The new models of CIP systems comes with many automatic controls and ...
    • Mejorar el Manejo de Materiales en Proyectos Utilizando Herramientas Lean 

      Díaz Marrero, Pedro J. (Polytechnic University of Puerto Rico, 2014)
      El proyecto consiste en mejorar el manejo de materiales en los proyectos. Esto implica que los materiales, sea de proyectos capitales o proyectos rutinarios, se encuentran en la necesidad del mismo programa. Es ...
    • Implementation of a New Membrane and the Re-use in a Tangential Flow Filtration System 

      Alonso, Sara V. (Polytechnic University of Puerto Rico, 2014)
      Tangential Flow Filtration (TFF) is commonly used as the last steps in protein purification processes at Biopharmaceutical Plants for clarification and concentration of the target protein. Since the membranes are ...