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dc.rights.licenseAll rights reserveden_US
dc.contributor.advisorMorales, José A.
dc.contributor.authorQuiñones Díaz, Mariely
dc.date.accessioned2021-08-18T12:36:47Z
dc.date.available2021-08-18T12:36:47Z
dc.date.issued2021
dc.identifier.citationQuiñones Díaz, M. (2021). Process Improvement and Cost Reduction Opportunities by a Change in the Packaging Material of Human Thrombin Component Coming in Vials [Unpublished manuscript]. Graduate School, Polytechnic University of Puerto Rico.en_US
dc.identifier.urihttp://hdl.handle.net/20.500.12475/1139
dc.descriptionDesign Project Article for the Graduate Programs at Polytechnic University of Puerto Ricoen_US
dc.description.abstractHuman Thrombin is a bleeding control agent that is formulated, filled into a glass vial, and lyophilized to maintain stability. In order to be shipped, the vials are packaged in a container made from cardboard material. Particulate matter coming from the packaging is transferred to the vials which results in the addition of a cleaning step prior to subsequent processing. An alternate plastic packaging material consisting of Polyethylene Terephthalate and Polypropylene was evaluated. Assessment of the cleaning process showed that a change in the current packaging represents an improvement in terms of the elimination of a non-value- added step and the associated labor cost. Additional evaluation demonstrates that this change also implies a reduction in scrap and in the costs applied for shipping. By identifying and implementing an alternate packaging material, product quality is improved, and non-value-added process steps and associated costs are eliminated, which will result in costs savings. Key Terms ⎯ Cleaning Process, Cost Reduction, Packaging Container, Particle Matteren_US
dc.language.isoen_USen_US
dc.publisherPolytechnic University of Puerto Ricoen_US
dc.relation.ispartofManufacturing Competitiveness Program;
dc.relation.ispartofseriesSpring-2021;
dc.relation.haspartSan Juanen_US
dc.subject.lcshPolytechnic University of Puerto Rico--Graduate students--Researchen_US
dc.subject.lcshPolytechnic University of Puerto Rico--Graduate students--Postersen_US
dc.subject.lcshCost controlen_US
dc.subject.lcshPackaging
dc.titleProcess Improvement and Cost Reduction Opportunities by a Change in the Packaging Material of Human Thrombin Component Coming in Vialsen_US
dc.typeArticleen_US
dc.rights.holderPolytechnic University of Puerto Rico, Graduate Schoolen_US


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