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Catheter bonding Process Improvements with High-intensity Ultraviolet Curing Systems
(Polytechnic University of Puerto Rico, 2021)
Ultraviolet (UV) curing is a common process used in medical devices manufacturing for bonding operations. Light-curable adhesives provide rapid cure, great adhesion, and good chemical resistance for sterilization processes. ...
Analytical Method Technology Transfer From Quality Control Laboratory To Manufacture Area
(Polytechnic University of Puerto Rico, 2021)
The project was developed with the intent to document the analytical transfer method to reduce in-process concentration testing cycle time. A reduction of up to 50% turnaround time (TAT) downtime was achieved. Waste reduction ...
Carnauba Dispenser to Improve Coated Tablets Elegance
(Polytechnic University of Puerto Rico, 2021)
This study describes the implementation of Six Sigma for improvement of the addition process of carnauba wax on coated tablets in a pharmaceutical industry. Due to the frequent complaints received from costumers for covered ...
Clean in Place Recipe Optimization
(Polytechnic University of Puerto Rico, 2021)
This improvement project was based in reduce the fixed tanks and transfer lines Clean in Place (CIP) recipe execution by consolidating the Water for Injection (WFI) rinse and the WFI CIP recipes into one single recipe. ...
Investigación Sobre “Sticking and Picking” en el Proceso de Compresión de Tabletas
(Polytechnic University of Puerto Rico, 2020)
El proceso de compresión de tabletas
es una innovación en el área de la tecnología de
manufactura. Dicho proceso provee la oportunidad
de tratar enfermedades produciendo fármacos con
dosis específicas para el remedio ...
Total Productive Maintenance (TPM) to Improve Laboratory Performance
(Polytechnic University of Puerto Rico, 2021)
Total Productive Maintenance is a methodology focused on the improvement of equipment performance. Is a concept mainly employed in the manufacturing operations in which the equipment performance is constantly monitored to ...
Sub Assembly Acceptance Optimization
(Polytechnic University of Puerto Rico, 2020)
A transactional process has the same
opportunities for improvement as a traditional
manufacturing process. This article provides a
successful example of how the tools and concepts of
Transactional Six Sigma can improve ...
Standard Work for Manufacturing Areas using Lean Methodology
(Polytechnic University of Puerto Rico, 2020)
Evaluating the structure of Batch
Record Review is an attempt to improve batch
release time. Many researches have been
implemented Lean methodology to reduce the cycle
time by automating the documentation process, ...
Lean Manufacturing Applied to In-Process Protein Concentration Determination Changing the Standard UV-Spectrometer for the Solo Variable Pathlength Extinction
(Polytechnic University of Puerto Rico, 2020)
The protein concentration test is a
complicated test, which requires a lot of time and
materials. Currently the test is being performed
using an old equipment of UV-Spectrometer
Visible. In this project, the researcher ...
Integrating DMADV Methodology to Develop a Dashboard Activities Tracker for a QC Laboratory
(Polytechnic University of Puerto Rico, 2020)
This article is focused on integrating
structured strategic quality management techniques
to improve operational results. DMADV (Define,
Measure, Analyze, Design and Verify) is the selected
methodology for the project ...