Fabrication and Characterization of 3D Printed Solid Oral Dosage Forms

Abstract

The pharmaceutical industry has been positively impacted by the 3D printing technique. Nevertheless, it has been poorly investigated. This study, was focused on fabricating solid oral dosage forms manufactured with corn and potato starch to obtain a 3D printed tablet. The starches underwent powder characterization to evaluate raw material conssitency. Subsequently, the starches were mixed with water as solvent and heat was applied to produce the starch-based inks used in the 3D printer. However, preliminar manufactured tablets showed poor uniformity in their characteristics. This study sheds light on improving the accessibility for the patient, waste reduction, and personalized medicine. Being able to fabricate a tablet utilizing biopolymers and 3D printing technique will contribute in an innovative way to society and to the pharmaceutical industry.