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    • CCL Label Puerto Rico process controls to maintain quality standards for high demanding pharmaceutical customer 

      Rivera Rosario, Joe Michael (Polytechnic University of Puerto Rico, 2023)
      Internal and external rejects are one of the common causes for a company to produce waste and therefore increase losses. Serving pharmaceutical clients requires the highest standards to produce quality and acceptable ...

    • Central Water-Cooled Chill Water Plant 

      Hernández, Daniel A. (Polytechnic University of Puerto Rico, 2015)
      A medical device facility in the island needs to determine the feasibility of replacing the existing air-cooled chilled water system at their main plant with a more efficient water-system in order to reduce the electric ...

    • Centralized Device Independent Software Architecture for the Internet of Things 

      Ruiz Linares, Luis (Polytechnic University of Puerto Rico, 2015)
      The Internet of Things (IoT) is growing stronger every year, as developers we need to get ready for the challenges ahead of us. It is getting hard for software developers to have a starting point for implementing new ...

    • CFD Study to Analyze the Behavior of Secondary Flow Using Fillets 

      Tafur Bermúdez, Lourdes (Polytechnic University of Puerto Rico, 2015)
      Secondary flow are a series of vortex created at the leading edge of the blade. These vortexes decrease the efficiency of the turbine by creating a non-uniform flow which will pass to successive blade stages. The ...

    • CFD-Based Method for Validation of DATCOMand Potential Flow Stability and Control Derivatives 

      Concepción Morales, Willie (Polytechnic University of Puerto Rico, 2021)
      DATCOM wasuse traditionally as the method to determine the aircraft downwash, and longitudinal stability and control derivatives for small unmanned air vehicles conceptual designat the Polytechnic ...

    • Challenges of Age Diversity in the Workplace 

      Chaluisant, Liz V. (Polytechnic University of Puerto Rico, 2014)
      Age diversity has become an important topic because four generations are currently working together for the first time in the United States. There is a lack of understanding between generations and succession plans are not ...

    • Change Control Process of the Planning Control Documents 

      Vega Rodriguez, Michelle (Polytechnic University of Puerto Rico, 2021)
      The Change Control Process of the Planning Control Documents (PCDs) for a manufacturing organization was manually coordinated and involved multiple entities with different change mechanisms. Therefore, the process was ...

    • Change Control Routed with Missing Information Delaying Approval and Implementation Date 

      Álvarez Rodríguez, Bianca (Polytechnic University of Puerto Rico, 2022)
      The approval of manufacturing change control for MedDevice Inc., is currently acting lower than target(15 business days). Based on a 12-months data review, the lead time of approval of a change is approximately ...

    • The change in airfare tickets based on the weekday and the continent 

      Santos Rodríguez, Gabriela (Polytechnic University of Puerto Rico, 2018)
      The purpose of this study is to help people understand the different theories that exist and to prove if any of the theories are actually effective when buying an airplane ticket. A research was conducted to have a ...

    • Change in the Precipitation Parameter Source and its Effect in Previously Designed Structures 

      Colón Collazo, Orlando J. (Polytechnic University of Puerto Rico, 2020)
      The impact of any development brings with it a series of changes to the environment that must be mitigated; thus, Hydrologic and Hydraulic Studies become necessary to bring solution at the design process. The ...

    • Changeover Process Optimization for a Medical Device Manufacturer in Haina, Dominican Republic 

      Gutierrez, Claudia (Universidad Politécnica de Puerto Rico, 2020)
      The medical device industry has the critical mission of saving and sustaining lives of patients being affected by chronical diseases. To these companies, having more available time to produce will enable and facilitate ...

    • Changeover Reduction Time by Adjusting the Cleaning Critical Parameters in Automated CIP Systems 

      Garay Charleman, Lynnette (Polytechnic University of Puerto Rico, 2018)
      Clean-In-Place (CIP) is a widely use process to clean biotechnology vessels contact surfaces. CIP is an automated cleaning method that involve minimum to no equipment disassembling thereby reducing labor and time ...

    • Characterization and Extrusion Qualification Process of Introducers/Dilators at Edwards Lifesciences Puerto Rico 

      Gonzalez Santiago, Nestor Alexis (Polytechnic University of Puerto Rico, 2022)
      Edwards Lifesciences is experiencing a high demand for Introducers/Dilators. The company decided to produce the Introducers/Dilators single lumen catheters shafts tubing in Añasco, Puerto Rico site. To implement this new ...

    • Chilled Water Plant Energy Upgrade 

      Cabrera Rivera, Cristian I. (Polytechnic University of Puerto Rico, 2022)
      This project was undertaken to increase the efficiency of the cooling equipment at the Nakamura Courthouse in Seattle, WA which is a building that is managed by the General Services Administration (GSA), the government ...

    • Chromatography Skid 3 Automation Integration Layer Upgrade 

      Figueroa Agosto, Delianne N. (Polytechnic University of Puerto Rico, 2023)
      This research will focus on upgrading the Chromatography System 3 to reduce time and generate batch reports. In this way, system monitoring is more effective and documentation is more accurate. The system handles an excessive ...

    • Clasificación ABC del Inventario de Materias Primas 

      Peña Richardson, Javier E. (Universidad Politécnica de Puerto Rico, 2020)
      La investigación se realizó en una empresa que elabora productos farmacéuticos, y surgió de la necesidad de clasificar el inventario de materias primas y aprovechar una expansión que se va a realizar, la cual afecta la ...

    • Clean in Place Recipe Optimization 

      Marin Alvarez, Crystal (Polytechnic University of Puerto Rico, 2021)
      This improvement project was based in reduce the fixed tanks and transfer lines Clean in Place (CIP) recipe execution by consolidating the Water for Injection (WFI) rinse and the WFI CIP recipes into one single recipe. ...

    • Clean Room Differential Pressure Monitoring Improvements 

      Vázquez Amaro, Luis J. (Polytechnic University of Puerto Rico, 2019)
      Manufacturing of oral solid dosage (OSD) forms, such tablets and capsules, is performed in a highly regulated environment. One of the guidelines used to provide the minimum requirements that a manufacturer must meet ...

    • Clean Steam Energy Conservation Process Design 

      Guevara Brugman, Kenneth L. (Polytechnic University of Puerto Rico, 2011)
      Abstract ― The objective of this article is to design the sterilization methodology and processes needed in a product or equipment that requires the injection of clean steam to create a sterile environment. Clean steam is ...

    • Cleaning Validation of a Manufacturing Line using CIP-100 Detergent and a Clean-in-place Skid System 

      Rivera Barreto, Deanceshka A. (Polytechnic University of Puerto Rico, 2022)
      Cleaning Validation is a prime element of control to the cross contamination and potential carry over topic at the manufacturing industry. This process must assure the quality, safety and efficiency of cleaning ...