Manufacturing Competitiveness
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Recent Submissions
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Design Improvement in the Workspace for Waste Reduction and Process Optimization
(Polytechnic University of Puerto Rico, 2023)In this current project will be demonstrated how a layout in the workspace can impact the efficiency of a process. An optimal design in the location of equipment and materials needed to execute a task can reduce all those ... -
Formulation Process Optimization
(Polytechnic University of Puerto Rico, 2023)The field of biologics drugs development continues to grow and is becoming increasingly competitive. The manufacturing of biological medicines is a complex process that consumes a large amount of resources and time ... -
Pull System for Material Replenishment in Manufacturing Sunshine Meds Design
(Polytechnic University of Puerto Rico, 2023)This project evaluates the material replenishment for manufacturing lines in Sunshine Meds Company who prepares medical devices kits in a manufacturing cleaning room. Opportunities were found looking into the material ... -
Diseño del Área del Manejador de Materiales Utilizando la Metodología Lean
(Polytechnic University of Puerto Rico, 2023)En la actualidad, el área de manufactura de cierta compañía no cuenta con un área de reabastecimiento de materiales. Lo que representa que el manejador de materiales tenga que recorrer más área de la normal para poder ... -
Desarrollo de Matriz de Complejidad y Mejoras a la Matriz de Destreza para Reducir la Fatiga en el Área Laboral
(Polytechnic University of Puerto Rico, 2023)La fatiga en el área laboral o los riesgos ergonómicos se deben principalmente a la ejecución de una estación de trabajo por un tiempo prolongado sin tener variaciones en las tareas que ejecuta. Los riesgos ergonómicos son ... -
Standardization Times in a Blending (Flex 2 Unit Operation) Manufacturing Process
(Polytechnic University of Puerto Rico, 2023)The continuous evolution in standardization, digitalization, and changes in the ways of working in manufacturing in the pharmaceutical industry and the increase in production for product X by 2023, has made it necessary ... -
Improvement in the Inventory System and How to Reduce Waste
(Polytechnic University of Puerto Rico, 2023)Due to the recent pandemic, industries have confronted inventory problems because of all the backorders that exist with the suppliers. Consequently, industries have lacked the necessary materials to continue their processes. ... -
Chromatography Skid 3 Automation Integration Layer Upgrade
(Polytechnic University of Puerto Rico, 2023)This research will focus on upgrading the Chromatography System 3 to reduce time and generate batch reports. In this way, system monitoring is more effective and documentation is more accurate. The system handles an excessive ... -
Implementación del Parámetro Tolerancia de Proceso en el Certificado de Calibración a Instrumentos Críticos del Área de Liofilización a Través del CMMS para Reducir las Investigaciones
(Polytechnic University of Puerto Rico, 2023)Los parámetros establecidos en los procesos de calibraciones son un factor crítico en la manufactura de productos farmacéuticos. A raíz de la alta incidencia de investigaciones para el departamento de calibración, se ... -
Optimization Design in the Production and Delivery Process of a Food Truck
(Polytechnic University of Puerto Rico, 2023)This abstract provides an overview of the optimization design strategies that can improve the production and delivery process of a food truck utilizing Lean Manufacturing and DMAIC methodology. A standardized menu, quality ... -
La Importancia de Procesos Lean en Auditorías Internas y Externas con el Fin de Identificar Mejoras en el Control de Calidad en Laboratorio Ambiental
(Polytechnic University of Puerto Rico, 2023)Cuando se trabaja por tantos años en el campo laboratorios lo que se busca mejorar los procesos que sean de satisfacción para cliente y empleado. El enfoque para una investigación sobre cómo mejorarlos sin que conlleve a ... -
Mejoras Al Diseño Establecido en el Proceso de Empaque para la Industria Biofarmacéutica con el fin de Minimizar Errores Humanos
(Polytechnic University of Puerto Rico, 2022)En una línea de manufactura, el 83.3% de los operadores concuerda con que el proceso de documentación es complejo, lo que aumenta la incidencia de errores humanos. El propósito de este estudio es identificar posibles ... -
Improvement in the Visibility of Nonconforming Product Inventory and Reduction
(Polytechnic University of Puerto Rico, 2022)One of the major problems reported in a company is the Nonconforming product inventory, reducing the availability to use space for new production lines and storage of conforming product. Company wants to understand why the ... -
Workflow Management in the Batch Record Review Process
(Polytechnic University of Puerto Rico, 2022)The review of Batch Records creates a story of the materials, manufacturing, and packaging involved in the production of biopharmaceuticals. The Master Batch Record details who, when, where, and how each process stage is ... -
Feasibility Study of Proposed Manufacturing Layout Re-design to Improve Process Capacity and Reduce Cycle Time of a Downstream Operation of Product A
(Polytechnic University of Puerto Rico, 2022)Lean Six Sigma tools and methodologies are widely used in today’s work environments. The use of a Lean Six Sigma approach provides organizations more flexibility and efficiency to improve their competitiveness. At the ... -
Optimization in the Account Registration Process in Automated Equipment
(Polytechnic University of Puerto Rico, 2022)Over the years technology has increased in the manufacturing areas. Companies have moved to obtain automated equipment for the manufacture of their products. In the pharmaceutical industry, this equipment has been implemented ... -
Designing a Standardized Process Flow for Regulatory R&D Service Center: A Design for Lean Six Sigma DMADV Case Study
(Polytechnic University of Puerto Rico, 2022)Lean Six Sigma has great impact in the removal of non-value-adding activities and improving business performance. It does so by applying tools and techniques to eliminate waste, and focus on implementing strategies to ... -
Mejoras de Calidad y Riesgos de EHS, mediante la Simplificación de Procesos y Detección Temprana para Minimizar Errores Humanos en los Procesos de la Industria de la Biotecnología
(Polytechnic University of Puerto Rico, 2022)Los errores cometidos en la industria farmacéutica son un hecho real el cual se debe atacar. Los equipos utilizados para la manufactura de medicamentos también requieren de un proceso de preparación, que incluyen limpieza ... -
Implementing Six Sigma Tools to Reduce Formulation Errors in a Compounding Pharmacy
(Polytechnic University of Puerto Rico, 2022)Formulation errors are medication errors that occur when a prescribed mixture is not performed as per the required medical order. Formulation errors in compounded total parenteral nutrition units represent an inherent ... -
Strategy for the Reduction of False Rejects in the Visual Inspection of Injectable Drug Products
(Polytechnic University of Puerto Rico, 2022)A hundred percent visual inspection is performed as part of the manufacturing process of injectable drug products as a regulatory requirement to detect and remove units with defects to protect the patients. The rejection ...
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