Browsing Manufacturing Engineering by Subject "Pharmaceutical industry"
Now showing items 1-8 of 8
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Applicability of Lean Concepts in Reducing Change Over Time to Increase Production Capacity
(Polytechnic University of Puerto Rico, 2011)Abstract - At this very competitive environment, companies need to do more with less. One way to do this is to maximize the use of the facilities that are already in use instead of building new ones or expanding existing ... -
Compression Machines Relocation for Space Optimization
(Polytechnic University of Puerto Rico, 2013)Pharmaceutical industries develop, produce and market drugs for use as medications. All pharmaceutical manufacturers are directed to produce in a high optimization environment to increase productivity and ensure product ... -
Development and Optimization for Generic Capsule Solid Oral Dosage Formulation Using Quality by Design (QbD) Principles
(Polytechnic University of Puerto Rico, 2015)Traditionally, the development and formulation of generic drugs has focused on the delivery of the product to the next phase of clinical study making the formulation design iterative and empirical. Furthermore, ... -
Implementation and Replacement of an Engineering Drawing Solution in a Pharmaceutical Manufacturing from an Information Technology Standpoint
(Polytechnic University of Puerto Rico, 2016)The pharmaceutical industry is a highly and strictly regulated environment. The quality, support and management of its processes and data generated are important aspects this type of industry needs to sustain. The ... -
Implementation of Electronic Logbooks for the Utilities Area in a Pharmaceutical Manufacturing Facility
(Polytechnic University of Puerto Rico, 2018)Technology is an ever evolving concept, that every year incorporates new terminology appropriate to technological advances and different application domains. Industries are trying to leverage all of those new concepts to ... -
Manufacturing Process Coordination through Visual Analytics Tools
(Polytechnic University of Puerto Rico, 2022)This research project was focused on the identification of requirements and the design of a software application toolset, which facilitates and improve the coordination of pharmaceutical manufacturing production steps. The ... -
Optimization of a Pharmaceutical Filling Process to Comply with Federal Regulations and Minimize Process Variability
(Polytechnic University of Puerto Rico, 2019)This article analyzes the scientific methodology that was followed to solve a problem that arose in a pharmaceutical installation after a federal regulatory inspection. The route for a robust solution was framed by a ... -
Wet Granulation End-Point Determination of a Drug Formulation
(Polytechnic University of Puerto Rico, 2019)Wet granulation is commonly used in oral solid dosage industry. The end-point is required to design a process that consistently meet products Critical Quality Attributes (CQAs) and the Critical Processing Parameters ...