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dc.rights.licenseAll rights reserveden_US
dc.contributor.advisorNieves Castro, Rafael A.
dc.contributor.authorSantos Pirela, Lorraine
dc.date.accessioned2022-03-31T19:27:44Z
dc.date.available2022-03-31T19:27:44Z
dc.date.issued2021
dc.identifier.citationSantos Pirela, L. (2021). Coating Process Improvement [Unpublished manuscript]. Graduate School, Polytechnic University of Puerto Rico.en_US
dc.identifier.urihttp://hdl.handle.net/20.500.12475/1427
dc.descriptionDesign Project Article for the Graduate Programs at Polytechnic University of Puerto Ricoen_US
dc.description.abstractAn increase in the number of events associated to AQLfailure that resulted on partial batch rejections was observed in 2020 for Tablets/Caplets formulations due to cosmetic conditions such as bump on coating, color blotches, pits on tablets, rough coating, lack of gloss, and odd shape tablets/caplets appearance. This report summarizes the coating improvements and recommendations identified to reduce the amount of pans inspected/rejected caused by aesthetical conditions. To improve the quality of process outputs identifiedthe team selected a quality managementmethod DMAIC (Define, Measure, Analyze, Improve, and Control). After using the methodology, the purpose of improving the cosmetic appearance of the product and decreasing the impacted pans was achieved. Data presented a significant reduction of pans inspection and rejection. Tablets pans impacted was reduced from 2.8% to 1.7%. Caplets pans impacted was reduced from 1.7% to 0.2%. KeyTerms⎯Coating, Improvement, Defects.en_US
dc.language.isoenen_US
dc.publisherPolytechnic University of Puerto Ricoen_US
dc.relation.ispartofManufacturing Competitiveness Program;
dc.relation.ispartofseriesWinter-2021;
dc.relation.haspartSan Juanen_US
dc.subject.lcshPolytechnic University of Puerto Rico--Graduate students--Researchen_US
dc.subject.lcshPolytechnic University of Puerto Rico--Graduate students--Postersen_US
dc.subject.lcshPharmaceutical industry--Quality control
dc.subject.lcshTablets (Medicine)--Quality control
dc.subject.lcshIbuprofen
dc.subject.lcshSix sigma (Quality control standard)
dc.titleCoating Process Improvementen_US
dc.typeArticleen_US
dc.rights.holderPolytechnic Universtiy of Puerto Rico, Graduate Schoolen_US


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