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dc.rights.licenseAll rights reserved
dc.contributor.advisorMóvil Cabrera, Omar A.
dc.contributor.authorMartínez, Vanessa
dc.contributor.authorJaime, Génesis
dc.contributor.authorVega, Gabriel
dc.contributor.authorCartagena, Reinaldo
dc.contributor.authorFalcón, Miguel
dc.date.accessioned2022-10-22T15:04:28Z
dc.date.available2022-10-22T15:04:28Z
dc.date.issued2022-10-13
dc.identifier.citationMartínez, V. & Jaime, G. (2022). From bio waste to bone substitute: 3D printing assisted fabrication of scaffolds containing high concentrations of eggshell derived hydroxyapatite [Research Poster]. Undergraduate Research Program For Honor Students HSI STEM Grant, Polytechnic University of Puerto Rico.en_US
dc.identifier.urihttp://hdl.handle.net/20.500.12475/1738
dc.descriptionFinal Research Poster for the Undergraduate Research Program for Honor Students HSI STEM Granten_US
dc.description.abstractAutografts are the gold standard for bone repair interventions due to their osteoinductive and osteoconductive properties Unfortunately, this technique entails important drawbacks such as limited availability and donor site morbidity Over the last few years, the scientific community has been developing different synthetic scaffolds as an alternative to autografts Despite the progress made in the field, there are still no ideal scaffolds with simultaneously good biocompatibility, porous three dimensional structures, bone conduction, osteoinduction, and osteogenesis Moreover, many of the proposed methods for the fabrication of scaffolds are difficult to customize to meet patient specific scaffold geometry Therefore, the present work aimed to incorporate additive manufacturing (AM or 3 D printing) in the fabrication of scaffolds containing high concentrations of eggshell derived hydroxyapatite (up to 60 wt The goal was to mimic the hard tissue composition of the human skeleton without affecting the mechanical stability of the scaffolds In order to achieve the main goal, hydroxyapatite ( was synthesized from waste eggshells via dry chemistry using ball milling In addition, porous sacrificial templates were fabricated via fused deposition modeling ( 3 D printing, which were subsequently filled with liquid/solid dispersions containing HAp and acrylonitrile butadiene styrene ( at different compositions After drying overnight, the sacrificial template was dissolved in water to finally obtain the scaffolds The fabricated materials were characterized via FTIR, microscopy, and compression test The most relevant results indicate that it was possible to use the proposed method to fabricate scaffolds with high content of hydroxyapatite (up to 60 wt of HAp) However, the high viscosity of the slurry containing 60 wt HAp created difficulties to fill properly the molds, resulting in fragile structures It was also observed that the compression modulus of the fabricated scaffolds increased with the presence of HAp into the ABS polymer matrix, obtaining the maximum value at 30 wt of HApen_US
dc.description.sponsorshipThis research project was supported by the HSI STEM Title III Polytechnic University of Puerto Rico “A Multifaceted Approach to Student Centered STEM Education” P031C210139en_US
dc.language.isoen_USen_US
dc.publisherPolytechnic University of Puerto Ricoen_US
dc.relation.ispartofSan Juan
dc.relation.ispartofseriesUndergraduate Research Program For Honor Students HSI STEM Grant 2021-2022
dc.subject.lcshPolytechnic University of Puerto Rico--Undergraduates--Posters
dc.subject.lcshBone substitutes
dc.subject.lcshThree-dimensional printing
dc.subject.lcshHydroxyapatite coating--Biocompatibility
dc.titleFrom Bio Waste to Bone Substitute: 3D Printing Assisted Fabrication of Scaffolds Containing High Concentrations of Eggshell Derived Hydroxyapatiteen_US
dc.typePosteren_US
dc.rights.holderPolytechnic University of Puerto Rico, Undergraduate Research Program for Honor Students HSI STEM Grant


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