Now showing items 168-187 of 1486

    • The change in airfare tickets based on the weekday and the continent 

      Santos Rodríguez, Gabriela (Polytechnic University of Puerto Rico, 2018)
      The purpose of this study is to help people understand the different theories that exist and to prove if any of the theories are actually effective when buying an airplane ticket. A research was conducted to have a ...
    • Change in the Precipitation Parameter Source and its Effect in Previously Designed Structures 

      Colón Collazo, Orlando J. (Polytechnic University of Puerto Rico, 2020)
      The impact of any development brings with it a series of changes to the environment that must be mitigated; thus, Hydrologic and Hydraulic Studies become necessary to bring solution at the design process. The ...
    • Changeover Process Optimization for a Medical Device Manufacturer in Haina, Dominican Republic 

      Gutierrez, Claudia (Universidad Politécnica de Puerto Rico, 2020)
      The medical device industry has the critical mission of saving and sustaining lives of patients being affected by chronical diseases. To these companies, having more available time to produce will enable and facilitate ...
    • Changeover Reduction Time by Adjusting the Cleaning Critical Parameters in Automated CIP Systems 

      Garay Charleman, Lynnette (Polytechnic University of Puerto Rico, 2018)
      Clean-In-Place (CIP) is a widely use process to clean biotechnology vessels contact surfaces. CIP is an automated cleaning method that involve minimum to no equipment disassembling thereby reducing labor and time ...
    • Characterization and Extrusion Qualification Process of Introducers/Dilators at Edwards Lifesciences Puerto Rico 

      Gonzalez Santiago, Nestor Alexis (Polytechnic University of Puerto Rico, 2022)
      Edwards Lifesciences is experiencing a high demand for Introducers/Dilators. The company decided to produce the Introducers/Dilators single lumen catheters shafts tubing in Añasco, Puerto Rico site. To implement this new ...
    • Chilled Water Plant Energy Upgrade 

      Cabrera Rivera, Cristian I. (Polytechnic University of Puerto Rico, 2022)
      This project was undertaken to increase the efficiency of the cooling equipment at the Nakamura Courthouse in Seattle, WA which is a building that is managed by the General Services Administration (GSA), the government ...
    • Chromatography Skid 3 Automation Integration Layer Upgrade 

      Figueroa Agosto, Delianne N. (Polytechnic University of Puerto Rico, 2023)
      This research will focus on upgrading the Chromatography System 3 to reduce time and generate batch reports. In this way, system monitoring is more effective and documentation is more accurate. The system handles an excessive ...
    • Clasificación ABC del Inventario de Materias Primas 

      Peña Richardson, Javier E. (Universidad Politécnica de Puerto Rico, 2020)
      La investigación se realizó en una empresa que elabora productos farmacéuticos, y surgió de la necesidad de clasificar el inventario de materias primas y aprovechar una expansión que se va a realizar, la cual afecta la ...
    • Clean in Place Recipe Optimization 

      Marin Alvarez, Crystal (Polytechnic University of Puerto Rico, 2021)
      This improvement project was based in reduce the fixed tanks and transfer lines Clean in Place (CIP) recipe execution by consolidating the Water for Injection (WFI) rinse and the WFI CIP recipes into one single recipe. ...
    • Clean Room Differential Pressure Monitoring Improvements 

      Vázquez Amaro, Luis J. (Polytechnic University of Puerto Rico, 2019)
      Manufacturing of oral solid dosage (OSD) forms, such tablets and capsules, is performed in a highly regulated environment. One of the guidelines used to provide the minimum requirements that a manufacturer must meet ...
    • Clean Steam Energy Conservation Process Design 

      Guevara Brugman, Kenneth L. (Polytechnic University of Puerto Rico, 2011)
      Abstract ― The objective of this article is to design the sterilization methodology and processes needed in a product or equipment that requires the injection of clean steam to create a sterile environment. Clean steam is ...
    • Cleaning Validation of a Manufacturing Line using CIP-100 Detergent and a Clean-in-place Skid System 

      Rivera Barreto, Deanceshka A. (Polytechnic University of Puerto Rico, 2022)
      Cleaning Validation is a prime element of control to the cross contamination and potential carry over topic at the manufacturing industry. This process must assure the quality, safety and efficiency of cleaning ...
    • Coating Process Improvement 

      Santos Pirela, Lorraine (Polytechnic University of Puerto Rico, 2021)
      An increase in the number of events associated to AQLfailure that resulted on partial batch rejections was observed in 2020 for Tablets/Caplets formulations due to cosmetic conditions ...
    • Coating Process Improvements in Solid Dose Form Manufacturing 

      Oquendo, María M. (Polytechnic University of Puerto Rico, 2013)
      Organization’s goals and objectives use strategic scorecards that include Quality, Economics, Speed and Culture to establish business metrics focused on building continuous future success and competitiveness to create ...
    • Coating Process Minor Changeover Reduction 

      Negroni Pedroza, Angel D. (Polytechnic University of Puerto Rico, 2020)
      During the Covid-19 Pandemic, many challenges arose that force healthcare companies to execute in new ways. Product demand was increased due to its effectiveness against the pandemic impact in the patients. To provide a ...
    • Cogeneration with Energy Sustainability Project for Bacardi Distillery 

      Saavedra Hernandez, Luis F. (Polytechnic University of Puerto Rico, 2021)
      At the Bacardi Distillery facilities in Puerto Rico, power outages are a problem that have affected rum production operations and costs. It has been identified that the cause of this problem is that the facilities do not ...
    • Combination Products Regulation – A Guide to Compliance 

      Cabranes, Leo R. (Polytechnic University of Puerto Rico, 2015)
      The Food and Drug Administration (FDA or Agency) has issued a regulation on the current good manufacturing practices (CGMP’s) requirements applicable to combination products. The new rule is intended to promote the ...
    • Commercial Daily Delinquency Report Automation for a Banking Institution in Puerto Rico 

      Garcés Rivera, Widalys (Polytechnic University of Puerto Rico, 2023)
      Commercial credit risk management entails the monitoring of key performance indicators, including delinquency ratios, for the commercial loan portfolio. The Commercial Credit Risk (CCR) team in a banking institution ...
    • Commissioning and Qualification of Utilities in a new Filling Line Expansion Project 

      Rivera Rivera, Francet L. (Polytechnic University of Puerto Rico, 2017)
      As part of a project for a Parenteral Filling Line expansion, Commissioning and Qualification activities were performed in new and existing modified systems to provide documented evidence and ensure that all equipment, ...
    • Company Moving to New Building After Hurricane Maria 

      Flores Morales, Jean C. (Polytechnic University of Puerto Rico, 2018)
      The main objective of this project is to move the operations of Pratt & Whitney Puerto Rico to a new building facility in Aguadilla by the end of Q2. The company was supposed to move by 9/2017, but Puerto Rico suffered ...