Browsing Design Project Articles Master Degree by Author "Torres, Edgar"
Now showing items 21-40 of 78
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Design of a Cleaning Change Over Reduction Strategy for a High Volume Product in a Packaging Line
Alvelo Ortiz, Grisel (Polytechnic University of Puerto Rico, 2010)Currently packaging operations are trying to reduce the downtime and operational cost among others activities to enhance efficiency and overall process performance. Based on this objective, pharmaceutical packaging ... -
Determination of Punches’ Lubrication Parameters for a Tablet Press Machine Using Single Tip Tooling Configuration to Compress an Analgesic Consumer Healthcare Product
Arroyo Sánchez, Jorge L. (Polytechnic University of Puerto Rico, 2012)The main goal of this engineering study is to determine a proper set of values for the lubrication interval parameters used for the punches of a tablet press machine. The values obtained will be referred as the starting ... -
Development and Evaluation of Prototype Heat Shrink Masking Machine
Candelario Quintana, Dary (Polytechnic University of Puerto Rico, 2016)This design project consists in developing a prototype equipment to reduce the heat variability produced by the current heat shrink installation process. A heat Shrink tubing is a shrinkable plastic tubing commonly ... -
Development of a Generic Pharmaceutical Solid Dosage Form Using Quality by Design (QbD)
López Torres, Luis A. (Polytechnic University of Puerto Rico, 2014)The Pharmaceutical Generic Sector has been growing over the past years and it is expected to surpass brand drugs in sale over next years. The FDA now recommends Quality by Design to develop Generic Drugs. The present work ... -
Development of Bulk Shipping Studies in Pharmaceutical Industry
Marrero Ruiz, Josean O. (Polytechnic University of Puerto Rico, 2012)Abstract ⎯ A bulk shipping study in the pharmaceutical industry consists in monitoring and analyzing the environmental conditions (e.g. temperature and relative humidity) during shipping and transportation of the drug ... -
Downtime Reduction Driven by Evaluation of Material Unavailability
Rivera Garcia, Danny (Polytechnic University of Puerto Rico, 2014)In the manufacturing & life-sciences industry, increased competition has forced a cost-reduction philosophy in what was once a highly profitable business. Manufacturers now need to maintain or improve time to market and ... -
Enfoque Estratégico para la Realización de Pruebas de Coeficiente de Reparto en el Desarrollo de Suplementos Dietéticos
Cruz Cruz, Christian H. (Polytechnic University of Puerto Rico, 2017)El aumento en sobrepeso de la población es una situación que ha estado arropando gran parte de la población mundial en especial a los países latinoamericanos. Esto acarrea consigo múltiples factores de riesgo y puede ... -
Engineering Standard Work Proficiency Reports Automation for the Aerospace Industry
Morales Quiles, Luis (Polytechnic University of Puerto Rico, 2012)Abstract - The study was conducted in an Aerospace Industry located in Isabela, Puerto Rico. The objectives of this project were to eliminate report errors and to reduce the report development from 5 days to less than 1 ... -
Engineering Study for the Feeding Operation Process of a Continuous Manufacturing Line
Classe Miranda, Gustavo (Polytechnic University of Puerto Rico, 2016)The use of continuous operations in solid-dosage manufacturing is growing rapidly and bringing benefits within pharmaceutical industry. One of the benefits that the continuous operation provides is that the development ... -
Equipment Validation Standardization for Project Implementation Time Reduction of Automated Manufacturing Platforms
Marín Román, José Xavier (Polytechnic University of Puerto Rico, 2012)Abstract - Medical Device regulated industry requires extensive validation work. Using the latest automation technology for the process equipment to eliminate the operator interaction brings the challenge of how fast the ... -
Evolutionary vs. Revolutionary: a Snap Shot of the Current Tendencies in Pharmaceutical Industry and the Impact of Process Analytical Technology and Continuous Manufacturing Processes
Aponte González, Amílcar (Polytechnic University of Puerto Rico, 2013)Food and Drug Administration (FDA) challenges the pharmaceutical industry to innovate itself and introduce ever higher quality standards through the use of technology. Development of continuous manufacturing systems ... -
Feasibility Evaluation and Quality Risk Management (QRM) for the Design of Automated Warehouse, Shipping and Transportation Operations
Caraballo Alvarez, Cynthia (Polytechnic University of Puerto Rico, 2013)Distributions center such as warehouse are important stage of storing materials, goods or products. Warehouses are important because they are created to store adequately the products as their main purpose. Warehouses ... -
Fill and finish Production Line End Effectors Improvements for Reducing Rejected Units due to Robot Pickup Failures
Figueroa Peterson, Juan José (Polytechnic University of Puerto Rico, 2014)Since the production of parenteral is more regulated and complicated, it makes the manufacture investment cost higher in comparison with other dosage forms. As result, is important to apply lean tools in order to reduce ... -
H&K Capsule Filling Equipment Reliability
Iglesias, Victor (Polytechnic University of Puerto Rico, 2013)Encapsulation is a process whereby the dose is charged into a hard gelatin capsule; powder, pellets, tablets or combinations of two or more of these may be filled into the capsules. Capsules provide a convenient way ... -
How Serialization can Improve Drug Manufacturing Operations
Santana Fortier, Joevan A. (Polytechnic University of Puerto Rico, 2017)An estimated 10% of the global medicine supply chain is counterfeit with sales of counterfeit prescription drugs estimated to be around $75 billion a year. Although estimates about the magnitude of the global ... -
HVAC Improvement for a Granulation Room of a Solid Dosage Manufacturer
Rodríguez Fernández, Yolanda (Polytechnic University of Puerto Rico, 2016)A pharmaceutical facility located in Vega Baja, Puerto Rico is dedicated to the manufacturing and packaging of prescription and consumer products that include tablets, caplets, capsules and powder for oral suspensions. ... -
Implementación de un Sistema Lean de Digitalización de Reportes en una Facilidad Universitaria
Córdova Morales, Iván R. (Polytechnic University of Puerto Rico, 2016)Se utiliza metodologías de Lean para evitar el gasto excesivo de papeles, utilizados en la impresión de los informes creados en la oficina de Sistemas de Información. Este método conlleva que las peticiones de los ... -
Implementation of Electronic Logbooks for the Utilities Area in a Pharmaceutical Manufacturing Facility
Ortiz Rivera, Elliot (Polytechnic University of Puerto Rico, 2018)Technology is an ever evolving concept, that every year incorporates new terminology appropriate to technological advances and different application domains. Industries are trying to leverage all of those new concepts to ... -
Implementation of Innovative Automated Coating Technology in a Medical Device Facility
Díaz Cruz, Teresa M. (Polytechnic University of Puerto Rico, 2012)Abstract - As part of new products development in a medical device plant, an innovative coating technology known as Physical Vapor Deposition (PVD) will be implemented for the electrode coating process. Current process is ... -
In Process Hardness Test Automation for Tablet Compression Process
Perez Garcia, Fernando L. (Polytechnic University of Puerto Rico, 2012)This article describes requirements to implement new hardness tester. The instrument was specifically for a dedicated product in the compression process area of a pharmaceutical operation. The challenge was to demonstrate ...