• español
    • English
    • Deutsch
  • English 
    • español
    • English
    • Deutsch
  • Login
View Item 
  •   PRCR Home
  • Polytechnic University of Puerto Rico
  • Design Project Articles Master Degree
  • Manufacturing Engineering
  • View Item
  •   PRCR Home
  • Polytechnic University of Puerto Rico
  • Design Project Articles Master Degree
  • Manufacturing Engineering
  • View Item
JavaScript is disabled for your browser. Some features of this site may not work without it.

Engineering Study for the Feeding Operation Process of a Continuous Manufacturing Line

Thumbnail
View/Open
Articulo Final_Gustavo Classe (974.9Kb)
Date
2016
Author
Classe Miranda, Gustavo
Metadata
Show full item record
Abstract
The use of continuous operations in solid-dosage manufacturing is growing rapidly and bringing benefits within pharmaceutical industry. One of the benefits that the continuous operation provides is that the development process turns to be easier and faster than in a batch operation. When designing a continuous manufacturing operation process, one of the challenges is the ability to consistently and continuously feed a powder into the downstream process. Variability in the flow rate of ingredients fed from powder feeders can change concentration of the process stream and propagate throughout the system ultimately leading to out of specification product [1] [2]. An engineering feeder study was conducted to establish the baseline process operation for each of the components while evaluating different operational conditions to ensure accuracy of the feeding process. Please include a summary of results related to critical process factors and responses. Key Terms - Continuous Manufacturing, Feeder, Gravimetric, Loss-in-Weight, Solids Dosage, Volumetric.
URI
http://hdl.handle.net/20.500.12475/510
Collections
  • Manufacturing Engineering

PRC Repository copyright © 2022  COBIMET, Inc.
Contact Us
Theme by 
Atmire NV
 

 

Browse

All of PRCRCommunities & CollectionsBy Issue DateAuthorsTitlesSubjectsThis CollectionBy Issue DateAuthorsTitlesSubjects

My Account

LoginRegister

Statistics

View Usage Statistics

PRC Repository copyright © 2022  COBIMET, Inc.
Contact Us
Theme by 
Atmire NV