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dc.rights.licenseAll rights reserveden_US
dc.contributor.advisorTorres, Edgar
dc.contributor.authorClasse Miranda, Gustavo
dc.date.accessioned2020-08-26T17:21:14Z
dc.date.available2020-08-26T17:21:14Z
dc.date.issued2016
dc.identifier.citationClasse Miranda, G. (2016). Engineering study for the feeding operation process of a continuous manufacturing line [Unpublished manuscript]. Graduate School, Polytechnic University of Puerto Rico.en_US
dc.identifier.urihttp://hdl.handle.net/20.500.12475/510
dc.descriptionDesign Project Article for the Graduate Programs at Polytechnic University of Puerto Ricoen_US
dc.description.abstractThe use of continuous operations in solid-dosage manufacturing is growing rapidly and bringing benefits within pharmaceutical industry. One of the benefits that the continuous operation provides is that the development process turns to be easier and faster than in a batch operation. When designing a continuous manufacturing operation process, one of the challenges is the ability to consistently and continuously feed a powder into the downstream process. Variability in the flow rate of ingredients fed from powder feeders can change concentration of the process stream and propagate throughout the system ultimately leading to out of specification product [1] [2]. An engineering feeder study was conducted to establish the baseline process operation for each of the components while evaluating different operational conditions to ensure accuracy of the feeding process. Please include a summary of results related to critical process factors and responses. Key Terms - Continuous Manufacturing, Feeder, Gravimetric, Loss-in-Weight, Solids Dosage, Volumetric.en_US
dc.language.isoen_USen_US
dc.publisherPolytechnic University of Puerto Ricoen_US
dc.relation.ispartofManufacturing Engineering;
dc.relation.ispartofseriesSpring-2016;
dc.relation.haspartSan Juanen_US
dc.subject.lcshContinuous improvement process
dc.subject.lcshPharmaceutical industry--Quality control
dc.subject.lcshPolytechnic University of Puerto Rico--Graduate students--Research
dc.titleEngineering Study for the Feeding Operation Process of a Continuous Manufacturing Lineen_US
dc.typeArticleen_US
dc.rights.holderPolytechnic University of Puerto Rico, Graduate Schoolen_US


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