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Now showing items 61-70 of 271
Understand and Correct the Weight Variability in Cases
(Polytechnic University of Puerto Rico, 2016)
Process variation in all manufacturing
processes will reflect a manufacturing production losses
since these variations reflect process waste. Understand
process variations and process capabilities is a key factor
when ...
Implementation and Replacement of an Engineering Drawing Solution in a Pharmaceutical Manufacturing from an Information Technology Standpoint
(Polytechnic University of Puerto Rico, 2016)
The pharmaceutical industry is a
highly and strictly regulated environment. The
quality, support and management of its processes
and data generated are important aspects this type
of industry needs to sustain. The ...
Using Lean Methodology to Reduce Changeover Time in Packing Line
(Polytechnic University of Puerto Rico, 2012)
Abstract - One of the metrics to measure efficiency in packing lines is Process Reliability (PR). It has been identified that the PR loss in packing Line X due to changeovers is 16%. The objective of this project is to use ...
Serialization and the Future of Product Traceability
(Polytechnic University of Puerto Rico, 2016)
Since the beginning of pharmaceutical
products and drugs, counterfeiting has been a
worldwide issue. Packed with minimal punishment,
illegal internet sales and unsecured physical
packaging, it has grown into an estimate ...
CSV Program Implementation using a Risk Based Approach to align ICH with GAMP5
(Polytechnic University of Puerto Rico, 2016)
it has been 29 years when Process
Validation was created. Since then there has been a
lot of creations of different types of validations.
During the years there have been a lot of
improvements in every validation ...
Using Design of Experiments to Characterize the Design Space of “Like-for- Like” Packaging Equipment
(Polytechnic University of Puerto Rico, 2015)
Industries with high volume demand
tend to have various equipments that can perform
the same task. Many of these tasks produce itemsthat
in order to sample them would require destroying
them. Validation is necessary ...
Cost Reduction in the Accumulator Process in Welding Operations
(Polytechnic University of Puerto Rico, 2015)
For the last few weeks, the heating,
ventilation, and air conditioning manufacturing
company Thermo King Arecibo has been increasing
the operational cost due to leak problems on the
accumulator area in the welding ...
Determination of Punches’ Lubrication Parameters for a Tablet Press Machine Using Single Tip Tooling Configuration to Compress an Analgesic Consumer Healthcare Product
(Polytechnic University of Puerto Rico, 2012)
The main goal of this engineering study is to determine a proper set of values for the lubrication interval parameters used for the punches of a tablet press machine. The values obtained will be referred as the starting ...
Mejorar el Proceso de Inspección Manual de Dosificación Sólida por un Sistema Automático
(Polytechnic University of Puerto Rico, 2015)
El proceso de producción de la tableta
de Tamper Resistant Formulation (TRF, por sus
siglas en inglés) conlleva una inspección visual de un
doscientos porciento requerida por el cliente. Esta
inspección visual en la ...
Quality Risk Management Strategies for Computer Systems Validation
(Polytechnic University of Puerto Rico, 2014)
Quality Risk Management is something
that has been gaining attention in the regulated
industry because it is listed as regulation in various
regulatory agencies such as FDA, ICH, ISO, ISPE
and other involved regulatory ...