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dc.rights.licenseAll rights reserveden_US
dc.contributor.advisorMorales, José A.
dc.contributor.authorTorres Colón, Luis Daniel
dc.date.accessioned2021-01-25T14:06:25Z
dc.date.available2021-01-25T14:06:25Z
dc.date.issued2020
dc.identifier.citationTorres Colón, L. D. (2020). Granulation area capacity increase [Unpublished manuscript]. Graduate School, Polytechnic University of Puerto Rico.en_US
dc.identifier.urihttp://hdl.handle.net/20.500.12475/1049
dc.descriptionDesign Project Article for the Graduate Programs at Polytechnic University of Puerto Ricoen_US
dc.description.abstractManufacturing pharmaceuticals are continuously looking for waste reduction to improve their processes and increase the manufacturing output. Granulation area capacity increase was evaluated for a solid dosage pharmaceutical industry in Las Piedras (LP), Puerto Rico. Volume increase for a pharmaceutical product is driving additional capacity requirement for granulation. Also, it was required to eliminate non-value added (NVA) tasks during the granulation activities. DMAIC process and its tools were used to increase the granulation capacity. Kaizen principles, process mapping and cycle efficiency, among others were used, providing a high-level view of the value stream being targeted in the improvement. Improvements such as new Ways of Working (WOW) to run two batches in parallel among others were actions implemented to granulation product capacity increase. As results of this project, the business benefits were a cost benefit of time saving 27% cycle time, representing 36 lots/month with a revenue of $1,947,886 per month. Key Terms ⎯ Benefits, Capacity Increase, DMAIC, Improvementen_US
dc.language.isoen_USen_US
dc.publisherPolytechnic University of Puerto Ricoen_US
dc.relation.ispartofManufacturing Competitiveness;
dc.relation.ispartofseriesSpring-2020;
dc.relation.haspartSan Juanen_US
dc.subject.lcshPolytechnic University of Puerto Rico--Graduate students--Researchen_US
dc.subject.lcshSix sigma (Quality control standard)
dc.subject.lcshPolytechnic University of Puerto Rico--Graduate students--Posters
dc.subject.lcshDrugs--Granulation
dc.titleGranulation Area Capacity Increaseen_US
dc.typeArticleen_US
dc.rights.holderPolytechnic University of Puerto Rico, Graduate Schoolen_US


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