Listar Manufacturing Engineering por título
Mostrando ítems 69-88 de 344
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Determination of In-Processing Manufacturing Impact into Elution Rate of Drug Eluting Steroid Collars
(Polytechnic University of Puerto Rico, 2012)Abstract - The Food and Drug Administration provides regulations for combination products. The medical device industry needs to comply with these regulations specifically in products containing drug. One of the many ... -
Determination of Punches’ Lubrication Parameters for a Tablet Press Machine Using Single Tip Tooling Configuration to Compress an Analgesic Consumer Healthcare Product
(Polytechnic University of Puerto Rico, 2012)The main goal of this engineering study is to determine a proper set of values for the lubrication interval parameters used for the punches of a tablet press machine. The values obtained will be referred as the starting ... -
Development and Evaluation of Prototype Heat Shrink Masking Machine
(Polytechnic University of Puerto Rico, 2016)This design project consists in developing a prototype equipment to reduce the heat variability produced by the current heat shrink installation process. A heat Shrink tubing is a shrinkable plastic tubing commonly ... -
Development and Optimization for Generic Capsule Solid Oral Dosage Formulation Using Quality by Design (QbD) Principles
(Polytechnic University of Puerto Rico, 2015)Traditionally, the development and formulation of generic drugs has focused on the delivery of the product to the next phase of clinical study making the formulation design iterative and empirical. Furthermore, ... -
Development of a Generic Pharmaceutical Solid Dosage Form Using Quality by Design (QbD)
(Polytechnic University of Puerto Rico, 2014)The Pharmaceutical Generic Sector has been growing over the past years and it is expected to surpass brand drugs in sale over next years. The FDA now recommends Quality by Design to develop Generic Drugs. The present work ... -
Development of a New Medical Device Production Line Using Systems Engineering
(Polytechnic University of Puerto Rico, 2012)Abstract - The design and development of a production line to manufacture a new medical device for clinical trials requires the establishment of a very precise implementation plan. This is especially important since we are ... -
Development of an Automated System for the Monitoring and Control pH and Conductivity of a Dampening Solution
(Polytechnic University of Puerto Rico, 2012)The influence of dampening solution parameters on the final printing quality has been remarked on many researches during the last decades. There are many parameters that need to be controlled on a fountain solution as pH, ... -
Development of Bulk Shipping Studies in Pharmaceutical Industry
(Polytechnic University of Puerto Rico, 2012)Abstract ⎯ A bulk shipping study in the pharmaceutical industry consists in monitoring and analyzing the environmental conditions (e.g. temperature and relative humidity) during shipping and transportation of the drug ... -
Development of Dual Drugs with Coated Microneedles
(Polytechnic University of Puerto Rico, 2022)Coated microneedles have been shown to deliver biopharmaceuticals and drugs into the skin in a minimally invasive manner. To increase patient acceptance, smaller needle diameters and lower insertion ... -
Development of Effectiveness Program through the Use of Productivity Metrics
(Polytechnic University of Puerto Rico, 2014)The Overall Plant Effectiveness Program has the purpose to improve the production capacity and optimize operations performance in an Active Pharmaceutical Ingredient (API) manufacturing plant. It requires a complete analysis ... -
Diseño de Optimización en el Proceso de Diseño en el Área de Moldeo por Inyección
(Polytechnic University of Puerto Rico, 2017)Mediante el uso de la metodología de Lean se reduce el tiempo de diseño y al mismo tiempo se eleva la calidad de producto que se hace en los moldes de inyección. Este método se aplicará haciendo una implementación de ... -
Diseño de Optimización en Logística de Organización
(Polytechnic University of Puerto Rico, 2018)El presente trabajo se desarrolló con la finalidad de implementar la metodología DMAIC Seis Sigma en conjunto a la de 5s, organizando y limpiando para reducir el tiempo que toma la búsqueda de materiales y herramientas ... -
Diseño de Proceso de Retorno de Componentes Funcionales de Dispositivos Médicos
(Polytechnic University of Puerto Rico, 2016)El uso de un dispositivo médico es más común día tras día. El constante aumento en producción aumenta además la acumulación de unidades fallidas en el área de manufactura. Cada proyecto de creación para una línea ... -
Diseño de Procesos de Mejora para obtener un “PMA” del FAA
(Polytechnic University of Puerto Rico, 2016)Actualmente existe mucha competencia entre compañías que realizan servicios similares, haciendo imperativo el buscar formas para poder mejorar los procesos de los productos que las mismas ofrecen, haciéndolos más ... -
Downstream Sampling Process Optimization
(Polytechnic University of Puerto Rico, 2014)The Downstream Sampling Process in the Biopharmaceutical industry is a timely and product consuming step. This process can be described as a highly labor intense due to all the required steps to collect a sample. In ... -
Downtime Reduction Driven by Evaluation of Material Unavailability
(Polytechnic University of Puerto Rico, 2014)In the manufacturing & life-sciences industry, increased competition has forced a cost-reduction philosophy in what was once a highly profitable business. Manufacturers now need to maintain or improve time to market and ... -
Effective Work Order Requests And Scheduling Tool Design for Maintenance Jobs
(Polytechnic University of Puerto Rico, 2020)A company located in Puerto Rico, which provides maintenance services and project management for various private properties, identified a problem of delays in maintenance work order response time and completion of ... -
Effectiveness of Push-Pull Method in a Hydraulic Sales Environment
(Polytechnic University of Puerto Rico, 2016)In today industry of sales, the main activity is to manage inventory in the fastest way possible. In the same way a warehouse main activity is to move the inventory from point a to point b in the fastest way without ... -
Electronic Report Improvement Using Six Sigma DMAIC Tools
(Polytechnic University of Puerto Rico, 2011)Abstract - The purpose of this project is to evaluate the application and benefits of Six Sigma tools to electronic reporting. In this particular case the DMAIC (Define, Measure, Analyze, Implement and Control) method is ... -
Electrospinning Process Capacity Optimization In Medical Device Industries
(Polytechnic University of Puerto Rico, 2021)As part of the manufacturing cost reduction initiatives that support 2021 Operational Excellence Projects to promote continuous improvement on medical device industries; the Electrospinning (E-spin) process was found with ...